Quantithermal Instruments | Waters Corporation offers a suite of reliable solutions that are essential for ensuring desired product quality and guaranteeing safety and efficacy in the biopharmaceutical industry. OurMicrocalorimetry, Thermal Analysis and Rheology solutions correspond to critical quality attributes (CQAs) that must be carefully measured for all kinds of biotherapeutics, including antibodies, cell and gene therapies, and vaccines. Biotherapeutics, unlike chemically synthesized drugs, can be heterogenous in nature and therefore require rigorous quality testing during development and manufacturing.
Characterization of biopharmaceuticals is accomplished with a panel of technologies to understand their basic chemical details:
- Binding affinity, specificity, and stoichiometry (ratio) to the molecular target
- Structure stability, and solvent environment stability.
- Higher Order Structure (HOS)
- Phase transitions
- Viscosity and viscoelastic behavior
- Residual moisture
Explore solutions from Quantithermal Instruments for biotherapeutics at different development stages. Click on each stage to learn how we can support your next-gen biotherapeutics.
